Melinda(詹妮弗·洛芙·休伊特 Jennifer Love Hewitt 饰)具有一种和鬼魂沟通的神秘能力,常常有鬼魂来找她帮忙。鬼魂们来到阳世,大都是因为有未尽的心愿,这些心愿阻止了他们再次获得生命,而Melinda在生与死之间穿梭,在帮助他们的同时,探索生命与死亡的真谛。知道真相的除了丈夫Jim(大卫·康拉德 David Conrad 饰)就是Melinda在古董店的合作伙伴Delia(卡穆琳·曼海姆 Camryn Manheim 饰)。喜欢研究超自然现象的人文历史大学教授Rick(杰·摩尔 Jay Mohr 饰),虽然看不到鬼魂,但是可以听到他们的声音,正因为此,他也经常帮助Melinda解释很多她看到的鬼魂给她的提示。
Chatfah, the youngest sister of the Bupphachinda family, has just received the largest share of her father's inheritance and is about to be married. However, Chatfah falls from the highest floor of a vacation home to her three older sisters' shocked eyes. When her body disappears, her three sisters—Baibua, Chomphu, and Picha—become suspects in her disappearance. The eldest sister Baibua is composed, wise, and has always sacrificed for her family. The second, Chomphu, is a confident model whose boyfriend Chatfah stole and was engaged to. The third, Putpichaya, is a jewellery designer and the closest to Chatfah. The three search for Chatfah while further tragedy befalls them following their youngest sister's disappearance. When no one else can be trusted, the three sisters must try to trust one another. They move back to their childhood mansion to find out who was behind Chatfah's disappearance, which could very well be one of them.
Season 4 will feature Bumpy Johnson as he continues his bloody war for control of Harlem against New York’s Mafia families, while contending with the emergence of a potential rival in newly arrived Black gangster Frank Lucas. After Malcolm X’s tragic death, Bumpy must also grapple with his daughter Elise’s involvement with the Black Panthers.