安德鲁(汤姆•汉克斯 Tom Hanks 饰)和米勒(丹泽尔•华盛顿 Denzel Washington 饰)认识于法庭上,两人都是年轻有为的律师,各为其主。然而,年轻的安德鲁不久后因为同性恋和身染艾滋病被老板发现,以莫须有理由解雇了。 遭解雇后的安德鲁四处寻找律师为他讨回公道。当安德鲁找到米勒时,米勒一开始拒绝了他。因为米勒像普通人一样憎恨同性恋和惧怕艾滋病,但当他看到安德鲁在图书馆搜索“艾滋病歧视”时遭到管理员的白眼,听着妻子缓慢而平静地说出他们的姨妈、朋友有很多也是同性恋时,他决定受理安德鲁的案件。 在最后的法庭上,病危的安德鲁毅然出庭……
Special Agent Alexander Connor is sent to investigate a house, from which a woman named Sandra has made numerous 911 calls. Things become more complicated than expected for Agent Connor, as he finds he must also rescue a police officer who responded to the home 24 hours earlier. Soon, Agent Connor will discover a horrifying secret; that Sandra is one of LUMEN CORPORATION's donors and has devoted her house to the corporation; a house which has been turned into a research lab for atrocious experiments performed on human beings.